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Malaguarnera, M., Bella, R., Vacante, M., Giordano, M., Malaguarnera, G., Gargante, M
This is a critical issue, as a decrease in muscle mass leads to a reduction in basal metabolic rate [41, 42], which could hinder the long-term benefits of obesity treatment by impairing the overall metabolic profile
The high discontinuation rate among patients without type 2 diabetes was striking, reinforcing concerns that insurance barriers limit sustained use for those seeking GLP-1 receptor agonists for weight management, Emanuel said
These receptors are involved in several important metabolic processes
It has become one of the most widely discussed regenerative peptides due to its broad healing potential
Additional at-risk groups include: Vegans and strict vegetarians , who may have low dietary B12 intake People with autoimmune conditions , including pernicious anaemia or type 1 diabetes Individuals with gastrointestinal conditions such as Crohn's disease or coeliac disease, which impair nutrient absorption People who have undergone bariatric surgery , which can significantly reduce B12 absorption Long-term users of proton pump inhibitors (PPIs) or H2-receptor antagonists , which reduce gastric acid and impair B12 release from food Those with a family history of either pernicious anaemia or diabetes For these groups, simultaneous monitoring of B12 status and glycaemic markers is particularly important to avoid diagnostic errors
